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circPLIN2 promotes clear cell renal cell carcinoma progression by binding IGF2BP proteins and miR-199a-3p

circPLIN2 promotes clear cell renal cell carcinoma progression by binding IGF2BP proteins and miR-199a-3p

June 29, 2025 Category: Blog

Abstract Recent evidence has indicated that circular RNAs (circRNAs), a novel type of regulatory RNA, play important roles in Trinket the development and progression of various cancers.However, the potential regulatory roles and molecular mechanisms of circRNAs in clear cell renal cell carcinoma (ccRCC) remain largely unclear.Here, we explored circ

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Targeting the MYCN-MDM2 pathways for cancer therapy: Are they druggable?

June 29, 2025 Category: Blog

Targeting oncogenes and their interactive partners is an effective approach to developing novel targeted therapies for cancer and other chronic diseases.We and others have long suggested the MDM2 oncogene being an excellent target for cancer therapy, based on its p53-dependent and -independent oncogenic activities in a variety of cancers.The MYC fa

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Blood test result communication in primary care: mixed-methods systematic review protocol

June 29, 2025 Category: Blog

Background: After testing, ensuring test results are communicated and actioned is important for patient safety, with failure or delay in diagnosis the most common cause of malpractice claims in primary care worldwide.Identifying interventions to improve test communication from the decision to test through to sharing of results has important implica

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AN OVERVIEW OF 10 YEARS OF QUALITATIVE METHODS AT JOURNAL OF INTERNATIONAL BUSINESS STUDIES

June 29, 2025 Category: Blog

This paper aims to present an overview of articles published in the Journal of International Business Studies (jibs), since 2003 till 2012.According to Web of Knowledge website, jibs is the most impacting publication focused in International Business.We analyzed Household Cleaning and Hygiene Products 498 articles in order to select papers built un

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